Anthelmintic activity of Alangium salviifolium bark

Alangium salviifolium (AS) is a novel medicinal plant used for the treatment of various diseases including helminthiasis by the traditional healers of Chhattisgarh. So an attempt has been taken to explore it scientifically. Preliminary phytochemical investigation reveals that there is presence of flavonoids, Saponins, phenols, bitter principles and steroids. Three different concentrations (50, 100 and 150 mg/ml) of crude extract of hexane, ethyl acetate, chloroform and methanol were tested against earthworms (Pheretima posthuma), which involved the evaluation of paralysis and death period of the worm. Methanol and chloroform extracts exhibited significant anthelmintic activity at highest concentration of 150 mg/mL. Piperzine citrate was selected as standard compound and DMF as control. The anthelmintic activity of Methanol and chloroform of bark of AS has therefore been evaluated for the first time.